…morbidity and mortality burden. Because patients with PAH have very variable responses to standard therapies which is difficult to predict, as well as monitoring the effectiveness of such therapies. The…
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miRNA Signatures for Pulmonary Hypertension
The technology relates to miRNA biomarkers to identify patients with pulmonary hypertension (PH), and sub-classify patients with pulmonary arterial hypertension (PAH) and chronic thromembolic PH (CTEPH). Proposed use The present…
Long-lasting nanoparticles for controlled release drug delivery
…in longevity and controlled drug release, preventing premature dispersal. Its robust performance in physiological conditions and its ability to facilitate a slow, regulated release make it a compelling choice for…
Ultrasound transducers and reconstruction methods for volumetric imaging
…Proposed use The proposed ultrasound imaging technology advances clinical ultrasound from 2D to more sophisticated 3D/4D imaging. It provides an economical solution for ultrasound imaging manufacturers, enabling the adoption of…
Novel inhibitors of NorA efflux pump for combating antimicrobial resistance
…bacteria to fluoroquinolone antibiotics or as a combination therapy with a fluoroquinolone antibiotic to treat a bacterial infection. Technology overview This invention identifies novel compounds to tackle antimicrobial resistance (AMR)….
Upcycling plastic waste into high-capacity sodium-battery anodes
…the cost of anode production. Anodes produced are compatible with both lithium-ion and sodium-ion batteries. Anodes has fast-charging capabilities, which is suitable to use in sodium-ion batteries. Anodes has high…
Filter system for the removal of haemolytic products from blood
…of this activity to maximise patient outcomes, hence this represents a significant market. Technology overview The present filter system is composed of a matrix embedded with human serum albumin, desferrioxamine…
Genetic constructs for localised population suppression of pest species
…with current interventions. Examples include populations of disease vectors, agricultural pests, or undesired invasive species. The types of pest species targetable may include, but is not limited to, insects, other…
Invariant Natural Killer T cell (iNKT cell) engagers
…is being developed as an ‘off-the-shelf’ option, without the need for genetic engineering, that can enhance the modularity of iNKT cells and thus their anti-tumour activity. Technology overview iNKT cell…
Lipid Nanoparticle Technologies: Thermostable RNA Formulations
…liquid or lyophilised form (commercial formulations: cryogenic storage at –70 °C/–20 °C). Simple one-pot, scalable manufacturing; biocompatible, non-toxic; FDA-approved compositions. The low-cost solution, and versatile applications for vaccines and targeted…
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