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Invariant Natural Killer T cell (iNKT cell) engagers

Invariant Natural Killer T cell (iNKT cell) engagers

…is being developed as an ‘off-the-shelf’ option, without the need for genetic engineering, that can enhance the modularity of iNKT cells and thus their anti-tumour activity. Technology overview iNKT cell…

Lipid Nanoparticle Technologies: Thermostable RNA Formulations

Lipid Nanoparticle Technologies: Thermostable RNA Formulations

…liquid or lyophilised form (commercial formulations: cryogenic storage at –70 °C/–20 °C). Simple one-pot, scalable manufacturing; biocompatible, non-toxic; FDA-approved compositions. The low-cost solution, and versatile applications for vaccines and targeted…

Cellular therapy for glaucoma

Cellular therapy for glaucoma

…glaucoma. Problem addressed NO is known to lower eye pressure, but NO is short lived and typically cleared within minutes, complicating drug delivery. For example, NO-donating eye drops like Vyzulta…

High-speed 3D Structured Illumination Microscopy (SIM)

High-speed 3D Structured Illumination Microscopy (SIM)

…improvement). This advancement is particularly advantageous for studying cell structures and mechanisms, such as observing endocytosis in Plasmodium malaria, monitoring calcium activity in dendritic spines, and examining the growth of…

An Inducible, multiplexed CRISPR system

An Inducible, multiplexed CRISPR system

…gRNA arrays Optimised for low burden Entire system delivered on single construct, compatible with all common lab strains Available with 10 selectable markers Intellectual property information Patent: WO 2023/148491  …

A real-time fluorescence probe for Heme Oxygenase activity

A real-time fluorescence probe for Heme Oxygenase activity

…protected and further research is underway to develop clinically validated diagnostic applications and compatible devices for using probes in numerous prioritised and clinically unmet indications. Intellectual Property Information The core…

System and method for real-time cochlear implant insertion control

System and method for real-time cochlear implant insertion control

…of interest based on impedance measurements. Benefits High positioning accuracy, sensitivity and precision compared to established monopolar impedance-based positioning method A less complex system compared to parylene photonics-based measurement setup…

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