A novel gene therapy for Huntington’s Disease that leverage zinc finger protein technology.
Technology Sectors & Industries
Therapeutics
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Catch up: Affordable technologies for an ageing society
Imperial.Tech.Pitch: Affordable technologies for an ageing society centred on the premise that within 20 years, there will be 25% fewer taxpayers to pensioners in the UK than in 2020.
HKMT Inhibitors
Small molecule inhibitors with potential for use in the treatment of neurodegenerative diseases such as Huntington’s disease, viral conditions such as HIV, and cancers
Aptamer-based multiplex screening platform
A fully flexible, scalable and low-cost detection platform to sense multiple protein targets simultaneously by grafting specific sequences along the backbone of a double-stranded DNA carrier.
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Professor Joshua B. Edel
Zinc finger therapy for Amyotrophic lateral sclerosis (ALS) and Frontotemporal dementia (FTD)
A zinc finger to target both the ALS and FTD therapeutically
Zinc finger therapy for Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS)
A zinc finger (zf) to target the FXTAS mutation therapeutically
Active delivery of Zinc Fingers for in vivo enhancement of gene regulation
A universal method to enhance control of gene expression in vivo with artificial gene-regulatory transcription factors (TFs).
A cytokine for wound healing and scar reduction
A cytokine that promotes wound healing by accelerating re-epithelialization of the wound bed faster than FDA approved products. The treatment also has a potential to minimise scarring after injury.
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