A filter matrix for use in the removal of haemoglobin, haem and free iron from the blood to combat poor patient outcomes resulting from haemolysis. Proposed use This technology could…
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Genetic constructs for localised population suppression of pest species
…with current interventions. Examples include populations of disease vectors, agricultural pests, or undesired invasive species. The types of pest species targetable may include, but is not limited to, insects, other…
Invariant Natural Killer T cell (iNKT cell) engagers
…engagers have been designed to harness the unique characteristics of iNKT cells, combining their innate and adaptive immune responses. Specifically, one form of iNKT cell engagers such as bispecific iNKT…
A catalyst for electrocatalytic oxidation of HMF to industrially valuable chemical products
…metal-free novel catalyst incorporating a TEMPO moiety. This allows for the electrocatalytic oxidation of HMF at pH 10, which is less alkaline compared to the metal oxide competitors on the…
Lipid Nanoparticle Technologies: Thermostable RNA Formulations
…liquid or lyophilised form (commercial formulations: cryogenic storage at –70 °C/–20 °C). Simple one-pot, scalable manufacturing; biocompatible, non-toxic; FDA-approved compositions. The low-cost solution, and versatile applications for vaccines and targeted…
Cellular therapy for glaucoma
…glaucoma. Problem addressed NO is known to lower eye pressure, but NO is short lived and typically cleared within minutes, complicating drug delivery. For example, NO-donating eye drops like Vyzulta…
High-speed 3D Structured Illumination Microscopy (SIM)
…improvement). This advancement is particularly advantageous for studying cell structures and mechanisms, such as observing endocytosis in Plasmodium malaria, monitoring calcium activity in dendritic spines, and examining the growth of…
An Inducible, multiplexed CRISPR system
…undesirable effects on their expression during transformation and handling without an inducer. This breakthrough opens avenues for studying essential genes and combinations thereof, potentially uncovering synthetic lethality relationships. Problem addressed…
A real-time fluorescence probe for Heme Oxygenase activity
…protected and further research is underway to develop clinically validated diagnostic applications and compatible devices for using probes in numerous prioritised and clinically unmet indications. Intellectual Property Information The core…
System and method for real-time cochlear implant insertion control
…of interest based on impedance measurements. Benefits High positioning accuracy, sensitivity and precision compared to established monopolar impedance-based positioning method A less complex system compared to parylene photonics-based measurement setup…
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