An AI tool for remote assessment of eczema severity for diverse skin types. Proposed use Eczema is an itchy, chronic inflammatory skin condition that affects approximately 20% of UK children…
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PROPHSY: Proteome in Pulmonary Hypertension Assay Score
…reproducibly inform prognosis independent of established prognostic factors NT-proBNP and 6-MWD. From the 30 proteins a weighted combination score of 6 biomarker proteins (selected by LASSO) was developed and validated…
miRNA Signatures for Pulmonary Hypertension
The technology relates to miRNA biomarkers to identify patients with pulmonary hypertension (PH), and sub-classify patients with pulmonary arterial hypertension (PAH) and chronic thromembolic PH (CTEPH). Proposed use The present…
Long-lasting nanoparticles for controlled release drug delivery
…solutions. For example, radiotherapeutics for labelling and diagnostics in PET sensing as well as chemotherapies. Problem addressed The technology confronts the instability of conventional drug delivery systems, which often degrade…
Ultrasound transducers and reconstruction methods for volumetric imaging
…3D/4D technologies across a range of clinical applications. By offering 4D imaging at a much lower hardware complexity and cost, this technology meets the growing market demand for advanced yet…
Novel inhibitors of NorA efflux pump for combating antimicrobial resistance
…bacteria to fluoroquinolone antibiotics or as a combination therapy with a fluoroquinolone antibiotic to treat a bacterial infection. Technology overview This invention identifies novel compounds to tackle antimicrobial resistance (AMR)….
Upcycling plastic waste into high-capacity sodium-battery anodes
…terephthalate (PET) plastic waste, including discarded plastic bottles, into high-performance anodes for batteries. This breakthrough has immense potential benefits for battery manufacturers, energy storage companies, and recycling industries, driving the…
Filter system for the removal of haemolytic products from blood
A filter matrix for use in the removal of haemoglobin, haem and free iron from the blood to combat poor patient outcomes resulting from haemolysis. Proposed use This technology could…
Genetic constructs for localised population suppression of pest species
…with current interventions. Examples include populations of disease vectors, agricultural pests, or undesired invasive species. The types of pest species targetable may include, but is not limited to, insects, other…
Invariant Natural Killer T cell (iNKT cell) engagers
…engagers have been designed to harness the unique characteristics of iNKT cells, combining their innate and adaptive immune responses. Specifically, one form of iNKT cell engagers such as bispecific iNKT…
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