Wide clip and applicator for minimally invasive surgery

Reference number 6687

Sectors: Medical Devices, Medtech

Industries: Medical Devices, Medical Technology

This technology relates to a new minimally invasive surgical instrument – a rotative surgical clip and applicator that allows the clamping of large anatomical areas for use in minimally invasive surgery.

Proposed use

  • Surgical device for minimally invasive surgery: (for example: bariatric surgery, benign upper GI surgery, hepatobiliary surgery, colorectal surgery, thoracic surgery)
  • Reinforcement of staple line
  • Closure of enterotomy
  • Control of vascular/biliary pedicles
  • Facilitate retraction of large organs

Problem addressed

Laparoscopic surgery often requires folds of tissue to be clamped together to occlude the flow of blood or other fluids through anatomical lumens – but existing clip applicators are not designed to achieve this, and can only deploy clips of limited width.

The tissues are held together by surgical clips which are deployed through the jaw of an applicator. The clip applicators contain a magazine of surgical clips that can be fired in succession. A conventional laparoscopic clip applicator system deploys a clip that has a standard profile with a nominal width of only 1mm. Although these surgical clips are ideal for ligating tubular structures, they are not designed to compress significant areas of tissue. In addition, when conventional clips are loaded into the jaw (which is longitudinal to the shaft of the instrument) it imposes a limit on the width of the clip to fit within the cross sectional footprint of the clip applicator. These challenges have been addressed by this innovative Wide Clip Applicator that will enhance the functionality of the laparoscopic clip with greater performance in tissue compression.

Technology overview

Key features of the Wide Clip and Applicator include:

  • The elongated clip with multiple bracings to allow for a greater degree of clamping force to be exerted on to the tissue being clamped together
  • The clip is single-braced with a T profile for large-area clamping of surgical anatomy
  • The bracing is aligned with the centreline of the clip applicator
  • The clip applicator is specifically designed using spring-loaded jaws and a tendon-based system to rotate the clip within the abdomen
  • Clips demonstrated superior clamping force and increased burst pressure resistance to standard ligation clips in ex vivo testing

An additional consideration of a rotatable clipping system is the need for features that not only retain the clips in the jaws of the device but that also allow torque to be transmitted to the clip in order for it to be rotated in a controlled manner. This design features improved clip retention, and ensures that the clip deforms in a controlled manner and it remains parallel under deformation. Plus, the design also allows the use of clips of variable lengths to support a variety of minimally invasive surgical procedures.


  • Enables the clamping of large anatomical area during minimally invasive surgery
  • The design of the clip applicator facilitates rotative movement inside the body
  • The elongated design of the clip ensures low deformity during clamping

Development Stage

  • 2nd prototype with improved functionality
  • Initial ex vivo characterisation of the clips has been performed


Watch the technology in action

Intellectual property information

An International PCT application (WO2018/069690) has been filed to protect the novel surgical clip and the applicator. The application is currently in national phase prosecution in the US and Europe.


Dr Mikael Sodergren

Clinical Senior Lecturer in Hepatopancreatobiliary Surgery
Faculty of Medicine, Department of Surgery & Cancer

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Contact us about this technology


Dr Amritha Nair

Industry Partnerships and Commercialisation Senior Executive, Faculty of Medicine

Dr Amritha Nair is an Industry Partnerships and Commercialisation Senior Executive in the Faculty of Medicine at Imperial College London. Amritha works across the entire innovation lifecycle from assessment, protection, and management of Intellectual property; marketing of technologies primed for commercialisation and supporting commercialisation via licensing or spinouts. Amritha also supports researchers in their bids for access to translational funding. Amritha manages an extensive IP portfolio, mainly focussed on therapeutics and diagnostics. Prior roles include innovation consulting for small and medium enterprises and handling the drug development and start-up activities for a private equity backed life science development group in Houston, USA. Amritha has a PhD in Molecular and Human Genetics from Baylor College of Medicine, Houston, USA and a MSc in Human Genetics from Sri Ramachandra University, Chennai, India.

Contact Amritha

[email protected]

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