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Portfolio of human colorectal adenocarcinomas

Portfolio of human colorectal adenocarcinomas

A portfolio of human colorectal adenocarcenoma cell lines including primary cell lines isolated from patients (of various Duke’s stages and histological grades) in addition to cloned cells lines genetically modified to highly express alpha integrin domains.

MyoLoop for cardiovascular research

MyoLoop for cardiovascular research

MyoLoop is a device that can simulate pathological conditions (e.g. hypertension), to study their progression, and the effects of therapeutic interventions on them.

Charcot-Marie Tooth Disease model

Charcot-Marie Tooth Disease model

Proposed use Research into Charcot-Marie Tooth Disease (Type 1A). Research into autoimmune neurological disorders would be the main target market. Problem addressed Construction of models of human inherited diseases is particularly important for testing gene therapy...

MicroRNA Biomarkers for ectopic or intrauterine pregnancy

MicroRNA Biomarkers for ectopic or intrauterine pregnancy

MicroRNA are important gene regulators and their expression profiles change with pathophysiology, allowing their use as biomarkers. Imperial researchers have identified differential markers that can distinguish pregnancy of unknown location (PUL).

Dr Rodrigo Ledesma Amaro

Dr Rodrigo Ledesma Amaro

Rodrigo Ledesma-Amaro is leading a research group at the interface of synthetic biology and metabolic engineering. His research lab is based in the Department of Bioengineering and the Center for Synthetic Biology and Innovation. He collaborates closely with Tom Ellis...

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