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CHORDs – Construction of highly ordered repetitive DNA sequences

CHORDs – Construction of highly ordered repetitive DNA sequences

CHORDS is a dual clustered regularly interspaced short palindromic repeats (CRISPR)/Golden gate assembly method for the construction of repetitive DNA sequences. This enables the construction of repetitive DNA sequences flanked by short (<30 base pairs) variable DNA regions. This strategy makes it possible to assemble and express guide RNA to be used in CRISPR mediated genetic modification.

Novel inhibitor of neuropathic pain

Novel inhibitor of neuropathic pain

This novel neutralising antibody-based approach offers an innovative and valuable therapeutic strategy for patients with neuropathic pain.

Dr Kenji Okuse

Dr Kenji Okuse

Research in our laboratory focuses on the molecular mechanism of pain pathways. We employ primary cultures of sensory neurons and macrophages, live cell imaging, and molecular biology.

Dr Anna Constantinou

Anna obtained a BSc in Chemistry from the Department of Chemistry at the University of Cyprus in 2014 and an MSc in Advanced Materials in 2015 from the Department of Materials at Imperial College. Her Masters thesis was entitled "Thermo-responsive Gels based on ABC...

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