
Professor Mark Isalan
Professor of Synthetic Biology
Faculty of Natural Sciences, Department of Life Sciences
Professor Mark Isalan's inventions

Novel treatment for Huntington’s Disease using zinc finger gene therapy
A novel gene therapy for Huntington’s Disease that leverage zinc finger protein technology. Further information on this technology

Zinc finger therapy for Amyotrophic lateral sclerosis (ALS) and Frontotemporal dementia (FTD)
A zinc finger to target both the ALS and FTD therapeutically Further information on this technology

Zinc finger therapy for Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS)
A zinc finger (zf) to target the FXTAS mutation therapeutically Further information on this technology

Active delivery of Zinc Fingers for in vivo enhancement of gene regulation
A universal method to enhance control of gene expression in vivo with artificial gene-regulatory transcription factors (TFs). Further information on this technology
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