Technology including intellectual property and knowhow, developed by the UK Gene Therapy Consortium, made up of researchers at Imperial College London, the University of Oxford and Edinburgh University has been…
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Portfolio of human colorectal adenocarcinomas
…alpha2 showed a significantly increased endrocrine and mucous cell lineage commitment relative to the parent cell line. Benefits Cell lines are invaluable tools for biomedical research. Cancer cell lines are…
MyoLoop for cardiovascular research
…myocardial slice (MS). The system is self-contained, and designed for chronic experiments, that is culture of myocardial slices. MyoLoop can simulate pathological conditions (e.g. hypertension), to study their progression, and…
DEP Trapping Using Metallised Nanopipettes
This invention enables efficient single molecule nanopore sensing at femtomolar concentrations using dielectrophoretic trapping by combining nanopore sensing and dielectrophoresis (DEP). Proposed use The relevant market for this technology is…
Nanotweezers for single-cell biopsy
…merely a ‘snapshot’ of the cell transcriptional profile at a particular point in time. Certain other techniques that enable a more dynamic study of single cells are limited by the…
Self-disinfecting appliances
…oxidants have limited shelf lives). Electronic control of the various components of the reactor are integrated into a single system. Benefits Environmentally friendly: Eliminates the need for packaging, storage and…
Charcot-Marie Tooth Disease model
Proposed use Research into Charcot-Marie Tooth Disease (Type 1A). Research into autoimmune neurological disorders would be the main target market. Problem addressed Construction of models of human inherited diseases is…
MicroRNA Biomarkers for ectopic or intrauterine pregnancy
…them to be used as biomarkers. The research team have focussed on microRNA expression in pregnancy of unknown location (PUL), a pregnancy classification which clinically precedes confirmation of either ectopic…
A cytokine for wound healing and scar reduction
…dressing materials. Problem addressed All injuries to the skin result in a scar after healing is complete – it is an inevitable side effect of wound repair. There are clear…
Methods to scale production of hPSC-derived endothelial cells
…endothelial cells in vitro under non-human animal derived component free conditions. The cells have a range of therapeutic applications (ex. Cell therapy and/or trans-plantation) Scalable production of large numbers of…
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