…patients or those with comorbidities. While more than 50% of DLBCL cases are cured with standard immuno-chemotherapy, patients who do not respond generally die from their disease. Technology overview The…
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Two distinct late stage preclinical lead series of highly specific inhibitors of MAP4K4
…MAP4K4 inhibitors can be commercialized to be used for protective agents against anthracycline therapy-induced cardiotoxicity. Additionally, MAP4K4 is a pivotal mediator of a number of key pathways and a target…
Octreotate Radioligand for Imaging Neuroendocrine Tumors
…the health. The radiotracer is detectable in the vascular compartment, liver, spleen, kidneys within first 6 minutes of radioligand injection. While retaining reasonably high binding affinity compared to existing clinically…
SmartFlap: 9% lower fuel costs for trucks from enhanced drag reduction
…Suitable for retro-fitting and new equipment Can be compliant with design and performance regulatory requirements Experimentally tested and clear understanding of the net energy savings Applications Truck trailers, rear and…
MOFsoft: software modelling for optimal MOF fabrication
…desired end cross-plane geometries. Even minor unwanted deformations in a small number of the channels can severely compromise a fibre’s optical performance, thus optimal manufacturing of MOFs requires an improved…
Use of valerate and bile salt hydrolase (BSH) as prevention and treatment for C. difficile infection
Proposed use Supplementation of C3-C10 short/medium chain fatty acids in combination with bile salt hydrolase (BSH) can be used for the therapeutic treatment of recurrent C. difficile infections or its…
Natural Killer – licensing a cell therapy
Imperial College London has licensed a new cell therapy technology to Australian company SUDA Pharmaceuticals. The technology, developed by Professor Tassos Karadimitrus and his team at Imperial’s Centre for Haematology,…
Graphene Fluidic exfoliation
Proposed use This proposed invention is a novel approach to liquid exfoliation to achieve more efficient and cost-effective production of 2D materials at any scale. The invention comprises the apparatus…
In-situ measurement for 2d-material exfoliation
…with many disadvantages including: invasive sampling, long time processing sample and slow turnaround time. These disadvantages can be addressed with smart production monitoring approach but this requires complex technical considerations….
Bioharmonophores for biomedical precision imaging
…generating bioharmonophores. Bioharmonophores are composed of both biodegradable and biocompatible components, self-assembling triphenylalanine peptides that are coated with poly(L-lactic acid) (PLLA) polymer. They can be readily surface functionalised with tumour…
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