Small molecule inhibitors with potential for use in the treatment of neurodegenerative diseases such as Huntington’s disease, viral conditions such as HIV, and cancers
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Aptamer-based multiplex screening platform
A fully flexible, scalable and low-cost detection platform to sense multiple protein targets simultaneously by grafting specific sequences along the backbone of a double-stranded DNA carrier.
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Professor Karen Polizzi
Professor Stuart Haslam
Professor Cleo Kontoravdi
Accelerated development of a potential treatment for cystic fibrosis
The UK Cystic Fibrosis Gene Therapy Consortium (GTC) is one of the partners in a licensing agreement with Boehringer Ingelheim.
Portfolio of human colorectal adenocarcinomas
A portfolio of human colorectal adenocarcenoma cell lines including primary cell lines isolated from patients (of various Duke’s stages and histological grades) in addition to cloned cells lines genetically modified to highly express alpha integrin domains.
Charcot-Marie Tooth Disease model
Proposed use Research into Charcot-Marie Tooth Disease (Type 1A). Research into autoimmune neurological disorders would be the main target market. Problem addressed Construction of models of human inherited diseases is particularly important for testing gene therapy...
A cytokine for wound healing and scar reduction
A cytokine that promotes wound healing by accelerating re-epithelialization of the wound bed faster than FDA approved products. The treatment also has a potential to minimise scarring after injury.
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