Professor Thomas Brand

Chair in Developmental Dynamics

Professor Thomas Brand's inventions

Zebrafish model for cardiac arrhythmia

Zebrafish model for cardiac arrhythmia

This fish line has been produced by gene editing and exhibits reduced cAMP binding associated with severe consequences. The fish mutant displays cardiac arrhythmia, muscular dystrophy and myofiber rupture and models a mutation found in patients with limb-girdle muscular dystrophy and AV-block. Further information on this technology

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